C2-Symmetric Chiral Supramolecular Hydrogels 2020-05-26

Our research focuses on the bottom-up construction of functional soft materials through supramolecular self-assembly. We specifically engineer C₂-symmetric chiral gelators, molecules with a unique two-fold symmetric axis of chirality, to create hydrogels with precisely defined hierarchical structures and emergent functions.

Chiral Biomaterials Engineering: Directing Cell Behavior and Enabling Diverse Biomedical Applications 2025-12-23

Our research focuses on a fundamental yet underexplored frontier in biomaterials science: how nanoscale chiral information from synthetic materials instructs biological systems. We engineer C₂-symmetric chiral supramolecular hydrogels to create precisely defined, water-rich 3D microenvironments that mimic the native extracellular matrix (ECM). This unlocks a new paradigm for designing advanced biomedical materials.

AI-Driven Chiral Materials Design: From Functional Prediction to Intelligent Development 2025-12-20

Our group is speeding up an integrated data-driven and intelligence-guided research paradigm for the next generation of chiral biomaterials. We aim to establish a closed-loop framework that bridges computational prediction, molecular design, experimental synthesis, and performance validation, with a targeted focus on programming chirality-mediated material-biological interactions.