Conformation-Matched Symbiotic Noncovalent Sites Facilitated Supramolecular Nanotwists Featuring both P and M Sub-Helical Domain 2025-10-28

Living system can use homochiral blocks to simultaneously fabricate diverse structures with opposite chirality (e.g., right-handed α-helices and left-handed polyproline-II helices) for maintaining three-dimensional conformations and functions of biostructures, but realizing this process in artificial systems remains exceptional challenge. 

Chiral Nanofibers of Camptothecin Trigger Pyroptosis for Enhanced Immunotherapy 2025-01-21

Camptothecin (CPT), a chemotherapeutic agent, demonstrates significant potential in cancer therapy. However, as a drug, CPT molecule suffers from poor water solubility, limited bioavailability, and insufficient immune response. 

Physical strategies to engineer supramolecular composite hydrogels for advanced biomedical applications 2025-01-09

Co-assembly is a key phenomenon in life, playing a significant role in various biological processes. In particular, supramolecular composite hydrogels (SMCHs) form through the incorporation of diverse functionalities via a co-assembly approach.