In Situ Heterochiral Helix Coupling Triggered Supramolecular Evolution 2026-02-12

In situ precise matching of chiral structures (e.g., stereocomplementary pairs between secondary structures of proteins) is essential for directing the evolution of biostructures.

Translating Supramolecular Design Principles to Camptothecin for Precision and Targeted Cancer Therapy 2026-01-30

This Account highlights our group's recent advances in chiral supramolecular materials for cancer therapy, which have pioneered a supramolecular engineering approach for CPT-based treatment. 

Conformation-Matched Symbiotic Noncovalent Sites Facilitated Supramolecular Nanotwists Featuring both P and M Sub-Helical Domain 2025-10-28

Living system can use homochiral blocks to simultaneously fabricate diverse structures with opposite chirality (e.g., right-handed α-helices and left-handed polyproline-II helices) for maintaining three-dimensional conformations and functions of biostructures, but realizing this process in artificial systems remains exceptional challenge.