A strategy for introducing biopotency-enhanced chirality coa... 2024-10-20

Biomedical magnesium alloys (Mg) are often considered potential metallic materials for bone repair scaffolds due to their excellent biomechanical properties, biocompatibility, and biodegradability. However, their rapid degradation behavior is insufficient to support the rapid growth and repair of living tissues.

Chiral Hydrogel Nerve Conduit Boosts Peripheral Nerve Regene... 2024-10-07

The Schwann cell (SC) is essential in peripheral nerve regeneration by reprogramming into a stem-like “repair Schwann cell” (rSC) phenotype; however, maintaining the rSC stemness remains an unmet challenge. 

Supramolecular Polymer Co-Assembled Multifunctional Chiral H... 2024-07-24

Amino acid-derived self-assembled nanofibers comprising supramolecular chiral hydrogels with unique physiochemical characteristics are highly demanded biomaterials for various biological applications. However, their narrow functionality often limits practical use, necessitating the development of biomaterials with multiple features within a single system.

Chiral-functionalized membranes for chiral drugs sieving 2024-05-11

Current trend that integrates chiral designs into robust membrane systems is providing distinct horizons for the development of chiral separation technology. However, creating chiral sites in-between membrane laminates is still an open issue.

Chiral Supramolecular Nanofibers Regulated Tumor-Derived Exo... 2024-02-16

Tumor-derived exosomes (TDEs) induced extracellular microenvironment has recently been validated to be critical for tumor progression and metastasis, however, remodeling it for oncotherapy still remains a major challenge due to difficulty in regulation of TDEs secretion.