Single-point halogenation regulates supramolecular chirality... 2021-10-22

The construction of chiral materials with precise chirality is of vital importance in biology and chemistry. Despite numerous chiral materials having been fabricated, it still remains a fundamental challenge to understand the chiral propensity with subtle changes of building blocks.

Biphenyl-Induced Superhelix in L-Phenylalanine-Based Supramo... 2021-10-04

Dynamic transitions of supramolecular assemblies between lower-order structures and higher-order superhelical structures (e.g., double-helical DNA, helical biopolymers) are of vital importance in many physiological processes, but still remain a great challenge to be realized in artificially assembled systems.

Chirality Bias Tissue Homeostasis by Manipulating Immunologi... 2021-10-03

The physiological chirality of extracellular environments is substantially affected by pathological diseases. However, how this stereochemical variation drives host immunity remains poorly understood.

Hydrogen-bonding regulated supramolecular chirality with con... 2021-07-16

The regulation of natural helical nanostructures is principally supported and actuated by hydrogen bonds (H-bonds) formed from hydrogen-bonding groups (peptide bonds and base pairs) to realize biological activities and specific biofunctional transformations.