Multistage Phase Programming in Fibrillated Peptide Coacerva... 2026-03-18

Natural protein condensates respond to external  stresses through stimuli-triggered multistage phase transitions. Reprogramming such transitions in synthetic systems is critical for rational design of self-adaptive materials with precisely regulated stimuli-responsiveness.

In Situ Heterochiral Helix Coupling Triggered Supramolecular... 2026-02-12

In situ precise matching of chiral structures (e.g., stereocomplementary pairs between secondary structures of proteins) is essential for directing the evolution of biostructures.

Translating Supramolecular Design Principles to Camptothecin... 2026-01-30

This Account highlights our group's recent advances in chiral supramolecular materials for cancer therapy, which have pioneered a supramolecular engineering approach for CPT-based treatment. 

Conformation-Matched Symbiotic Noncovalent Sites Facilitated... 2025-10-28

Living system can use homochiral blocks to simultaneously fabricate diverse structures with opposite chirality (e.g., right-handed α-helices and left-handed polyproline-II helices) for maintaining three-dimensional conformations and functions of biostructures, but realizing this process in artificial systems remains exceptional challenge due to difficulty in constructing precise noncovalent pattern for diverse chirality transfer.